{"id":2196,"date":"2023-03-29T20:09:55","date_gmt":"2023-03-29T20:09:55","guid":{"rendered":"https:\/\/healthnews.zone\/?p=2196"},"modified":"2023-03-29T20:09:55","modified_gmt":"2023-03-29T20:09:55","slug":"astonishing-molecular-syringe-ferries-proteins-into-human-cells","status":"publish","type":"post","link":"https:\/\/healthnews.zone\/?p=2196","title":{"rendered":"\u2018Astonishing\u2019 molecular syringe ferries proteins into human cells"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Technique borrowed from nature, and honed using artificial intelligence, could spur the development of better drug-delivery systems.<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"data:image\/svg+xml,%3Csvg%20xmlns='http:\/\/www.w3.org\/2000\/svg'%20viewBox='0%200%20370%20247'%3E%3C\/svg%3E\" data-lazy-src=\"https:\/\/healthnews.zone\/wp-content\/uploads\/2023\/03\/image-91.png\" alt=\"\" class=\"zeen-lazy-load-base zeen-lazy-load wp-image-2197\"\/><noscript><img decoding=\"async\" width=\"767\" height=\"511\" src=\"https:\/\/healthnews.zone\/wp-content\/uploads\/2023\/03\/image-91.png\" alt=\"\" class=\"wp-image-2197\" srcset=\"https:\/\/healthnews.zone\/wp-content\/uploads\/2023\/03\/image-91.png 767w, https:\/\/healthnews.zone\/wp-content\/uploads\/2023\/03\/image-91-300x200.png 300w, https:\/\/healthnews.zone\/wp-content\/uploads\/2023\/03\/image-91-370x247.png 370w, https:\/\/healthnews.zone\/wp-content\/uploads\/2023\/03\/image-91-293x195.png 293w, https:\/\/healthnews.zone\/wp-content\/uploads\/2023\/03\/image-91-120x80.png 120w, https:\/\/healthnews.zone\/wp-content\/uploads\/2023\/03\/image-91-240x160.png 240w, https:\/\/healthnews.zone\/wp-content\/uploads\/2023\/03\/image-91-390x260.png 390w\" sizes=\"(max-width: 767px) 100vw, 767px\" \/><\/noscript><figcaption class=\"wp-element-caption\">The bacterium\u00a0<em>Photorhabdus asymbiotica\u00a0<\/em>uses molecular spikes to pierce a hole in the membranes of host cells.Credit: F. Zhang\u00a0<em>et al.\/Nature<\/em><\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Researchers have hijacked a molecular \u2018syringe\u2019 that some viruses and bacteria use to infect their hosts, and put it to work&nbsp;<a href=\"https:\/\/www.nature.com\/subjects\/protein-delivery\">delivering potentially therapeutic proteins<\/a>&nbsp;into human cells grown in the laboratory.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cIt\u2019s astonishing,\u201d says Feng Jiang, a microbiologist at the Chinese Academy of Medical Sciences Institute of Pathogen Biology in Beijing. \u201cIt is a huge breakthrough.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The technique, published in\u00a0<em>Nature<\/em>\u00a0on 29 March<sup><a href=\"https:\/\/www.nature.com\/articles\/d41586-023-00922-4#ref-CR1\">1<\/a><\/sup>, could offer a new way to administer protein-based drugs, but will need more testing before it can be used in people. With further optimization, the approach might also be useful for delivering the components needed for\u00a0<a href=\"https:\/\/www.nature.com\/subjects\/crispr-cas-systems\">CRISPR\u2013Cas9 genome editing<\/a>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Read more here: <a href=\"https:\/\/www.nature.com\/articles\/d41586-023-00922-4\">https:\/\/www.nature.com\/articles\/d41586-023-00922-4<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Technique borrowed from nature, and honed using artificial intelligence, could spur the development of better drug-delivery systems. Researchers have hijacked a molecular \u2018syringe\u2019 that some viruses and bacteria use to infect their hosts, and put it to work&nbsp;delivering potentially therapeutic proteins&nbsp;into human cells grown in the laboratory. \u201cIt\u2019s astonishing,\u201d says Feng Jiang, a microbiologist at the Chinese Academy of Medical Sciences Institute of Pathogen Biology in Beijing. \u201cIt is a huge breakthrough.\u201d The technique, published in\u00a0Nature\u00a0on 29 March1, could offer [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[16],"tags":[],"class_list":["post-2196","post","type-post","status-publish","format-standard","hentry","category-medication"],"_links":{"self":[{"href":"https:\/\/healthnews.zone\/index.php?rest_route=\/wp\/v2\/posts\/2196","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthnews.zone\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthnews.zone\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthnews.zone\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/healthnews.zone\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2196"}],"version-history":[{"count":1,"href":"https:\/\/healthnews.zone\/index.php?rest_route=\/wp\/v2\/posts\/2196\/revisions"}],"predecessor-version":[{"id":2198,"href":"https:\/\/healthnews.zone\/index.php?rest_route=\/wp\/v2\/posts\/2196\/revisions\/2198"}],"wp:attachment":[{"href":"https:\/\/healthnews.zone\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2196"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthnews.zone\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2196"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthnews.zone\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2196"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}