Scientists disable protective gene in mosquitoes, making them susceptible to disease

Kevin Myles, Ph.D., Department of Entomology professor, with containers of mosquitoes used in his research. Myles latest study revealed immune pathways that could be disabled making the mosquitoes more susceptible to the diseases they carry and pass to humans. Credit: Michael Miller

Immune pathways that protect mosquitoes from human pathogens, including West Nile, Zika and dengue viruses were disabled by Texas A&M AgriLife Research scientists.

The research study, “RNA interference is essential to modulating the pathogenesis of mosquito-borne viruses in the yellow fever mosquito Aedes aegypti,” published in the Proceedings of the National Academy of Sciences, showed that the mosquito vector species Aedes aegypti becomes acutely susceptible to disease when the protective immune pathway is disabled.

Read more here: https://phys.org/news/2023-03-scientists-disable-gene-mosquitoes-susceptible.html